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Pfizer Announces Positive Phase 3 Results of ADCETRIS Regimen in DLBCL

Shows significant improvement in primary endpoint of overall survival and secondary endpoints of progression free survival and overall response rate.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Pfizer announced that a Phase 3 study of the antibody-drug conjugate ADCETRIS (brentuximab vedotin) in combination with lenalidomide and rituximab for the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) showed a statistically significant and clinically meaningful improvement in overall survival (OS) compared to lenalidomide and rituximab plus placebo. Positive outcomes were also observed in key secondary endpoints, including progression free survival (PFS) an...

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